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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HADHA
All Species:
22.12
Human Site:
S573
Identified Species:
44.24
UniProt:
P40939
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40939
NP_000173.2
763
83000
S573
V
D
P
K
K
L
D
S
L
T
T
S
F
G
F
Chimpanzee
Pan troglodytes
XP_515339
763
82965
S573
V
D
P
K
K
L
D
S
L
T
T
S
F
G
F
Rhesus Macaque
Macaca mulatta
XP_001086472
763
83034
S573
V
D
P
K
K
L
D
S
L
T
T
S
F
G
F
Dog
Lupus familis
XP_532894
762
82917
S573
V
E
P
K
K
L
D
S
L
T
T
S
F
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMS1
763
82651
A573
V
D
P
K
K
L
D
A
L
T
T
G
F
G
F
Rat
Rattus norvegicus
Q64428
763
82646
A573
V
D
P
K
K
L
D
A
L
T
T
G
F
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508292
763
82918
S573
V
E
P
K
K
L
D
S
L
T
T
S
F
G
F
Chicken
Gallus gallus
NP_990387
770
83168
A580
I
D
P
K
K
V
D
A
I
S
T
A
F
G
F
Frog
Xenopus laevis
NP_001085618
760
82341
A570
V
D
P
K
K
L
D
A
L
S
T
G
F
G
F
Zebra Danio
Brachydanio rerio
NP_001082906
763
82870
S573
T
D
P
K
K
L
D
S
L
T
T
G
F
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609299
783
84056
Q585
V
D
P
K
D
L
D
Q
Y
T
K
K
F
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192117
703
75892
V539
V
G
L
R
Q
G
K
V
I
I
V
V
G
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
89.6
N.A.
86.5
85.1
N.A.
85.5
77.2
77.4
72.3
N.A.
54.6
N.A.
N.A.
59.5
Protein Similarity:
100
99.8
99.3
95.1
N.A.
94
93.5
N.A.
92.4
87.9
89.2
84.8
N.A.
71.3
N.A.
N.A.
72.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
60
80
86.6
N.A.
66.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
93.3
86.6
N.A.
66.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
34
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
9
0
92
0
0
0
0
0
0
9
0
% D
% Glu:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
92
0
92
% F
% Gly:
0
9
0
0
0
9
0
0
0
0
0
34
9
92
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
17
9
0
0
0
0
0
% I
% Lys:
0
0
0
92
84
0
9
0
0
0
9
9
0
0
0
% K
% Leu:
0
0
9
0
0
84
0
0
75
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
17
0
42
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
75
84
0
0
0
0
% T
% Val:
84
0
0
0
0
9
0
9
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _